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Mucosal Healing Ulcerative Colitis Studies

mucosal healing colon
Mucosal Lining of the Colon

One of the most common questions we all ask ourselves is with regards to the healing of colon.  Some of us might refer to it as mucosal healing.  Especially when we are in the middle of a nasty flare up and maybe even more when we have just gotten out of a nasty period of active symptoms and bleeding.

There is all sorts of different data and methods of determining “how much” or “how little” the colon has actually healed.  Sometimes its easier to find out what’s really happening when we go in for a colonoscopy, but come one, that’s not easy is it…

So what the heck are the recent news articles or published studies saying about the health of our colon?  What are the studies recommending as to best practices for colitis patients?  How best can we reach quality healing of the inner membranes of our colon?

I’ve decided that its time to do some searching for recent studies on the topic of mucosal healing and present them in a list below for all of you to read about.  Feel free to read further on any of the studies for the full text versions.  Some of which have great detail into how, why, and if certain colitis therapies are potentially better than others to reach this goal.

  1. Histological healing favors lower risk of colon carcinoma in extensive ulcerative colitis
  2. Frequency and prognostic role of mucosal healing in patients with Crohn’s disease and ulcerative colitis after one-year of biological Therapy  (The conclusion from this article I found pretty amazing: Mucosal healing did not predict sustained clinical remission in patients in whom the biological therapies had been stopped.)
  3. Clinical Study of the Relation between Mucosal Healing and Long-Term Outcomes in Ulcerative Colitis  (Dr. Kaoru Yokoyama from the Department of Gastroenterologist, Kitasato University School of Medicine, Japan)

  4. Predictors of Endoscopic Inflammation in Patients with Ulcerative Colitis in Clinical Remission  (So many of us, probably myself included at many times along the way in the past 6 years since my UC diagnosis may feel that we are in clinical remission, BUT, does that mean the the insides of our colons are looking perfectly pink as well?, this study addresses this in some interesting ways)