One of the most common medications that doctors prescribe for ulcerative colitis patients is Asacol. This medications is a 5-ASA drug that is currently the only sulfa free medication approved to treat UC. As far as the pyramid for treating UC goes, asacol is one of the less hard-core drugs compared to some others that are prescribed.
Unfortunately, not everyone responds well to asacol. Myself for example did not have any positive response at all to the medication, and that is the reason why my doctor told me to stop taking it, and moved me over to take colazal which as well is a nother 5-ASA drug, and as well that one did not work for me either.
It is not really known exactly why Asacol can work form some people and not work for others. As this medication is taken orally, and the medicine is supposed to be helping out the colon, there is always a chance that the medicine is digested before making its way to the colon. The actual medicine though claims to have a delayed release so it will not be broken up until it reaches the colon…
At the end of the day, Asacol does work for some colitis patients, it doesn’t work for everyone, it is relatively side effect free, so if your doctor prescribes it to you, its a pretty safe thing to test out. Or at least, I have not had any bad reactions to it, and have not met anyone who has gotten very sick from the Asacol pills. If you are stuck taking this medication for a long time and are not seeing any improvement and are getting worse with your colitis symptoms, definitely talk to your doctor about it.